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CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family.
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What do CXC chemokines do?
The CXC family of chemokines and their receptors are crucial for inflammation and antitumor immunity, which are key factors in CRC progression. These small proteins are secreted not only by tumor cells but also by leukocytes, fibroblasts, endothelial cells and epithelial cells.
What is a chemokine receptor?
Chemokine receptors are cytokine receptors found on the surface of certain cells that interact with a type of cytokine called a chemokine. There have been 20 distinct chemokine receptors discovered in humans.
What is CXCR3 a marker for?
CXCR3 expression has been proposed as a reliable marker for T memory responses, as viral recall responses for both CD8+ and CD4+ T cells are largely restricted to CXCR3+ cells [74, 76].
What is CXCR4 a marker for?
Chemokine Receptor CXCR4 Is a Novel Marker for the Progression of Cutaneous Malignant Melanomas - PMC.
CC chemokine receptors (or beta chemokine receptors) are integral membrane proteins that specifically bind and respond to cytokines of the CC chemokine ...
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Chemokine receptors are cytokine receptors found on the surface of certain cells that interact with a type of cytokine called a chemokine.
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Chemokines or chemotactic cytokines, are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, ...
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C-X-C chemokine receptor type 4 (CXCR-4) also known as fusin or CD184 (cluster of differentiation 184) is a protein that in humans is encoded by the CXCR4 gene.
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01.07.2020 · Chemokines and their receptors mediate cell migration, which influences multiple fundamental biological processes and disease conditions ...
01.12.2022 · CXC chemokine receptors bind to cytokines of the CXC chemokine family. CXCR4 is specific for Stromal Derived Factor 1 (SDF-1α, known also as ...
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