28.12.2023 · Together, these data support a model in which PDAC malignant cell-secreted TGF-β activates EGFR signaling in myCAFs in murine and human PDAC.
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What are the characteristics of a cancer cell?
Morphologically, the cancerous cell is characterized by a large nucleus, having an irregular size and shape, the nucleoli are prominent, the cytoplasm is scarce and intensely colored or, on the contrary, is pale.
What is the mechanism of cancer?
Cancer is a multi-step process during which cells undergo profound metabolic and behavioural changes, leading them to proliferate in an excessive and untimely way, to escape surveillance by the immune system, and ultimately to invade distant tissues to form metastases [1].
What is the development of cancer?
It starts to grow and divide out of control instead of dying when it should. They also don't mature as much as normal cells so they stay immature. Although there are many different types of cancer, they all start because of cells that are growing abnormally and out of control. Cancer can start in any cell in the body.
Stable suppression of tumorigenicity by virus-mediated RNA interference
pubmed.ncbi.nlm.nih.gov › ...
These results indicate that viral delivery of small interfering RNAs can be used for tumor-specific gene therapy to reverse the oncogenic phenotype of cancer ...
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11.10.2021 · Explanations about what cancer is, how cancer cells differ from normal cells, and genetic changes that cause cancer to grow and spread.
12.09.2023 · The resource can help researchers uncover new molecular insights into how cancers develop and progress. Microscope image of chromosomes ...
My lab's work has propelled new questions to the forefront of cancer research, with the unexpected discovery of the mechanisms that allow dormant breast cancer ...
Alphabetical list of all cancers, with links to disease-specific and general information about treatment, coping, screening, prevention, clinical trials, ...
Cancer Cell International publishes articles on all aspects of cancer cell biology originating from work using laboratory experimentation. The journal ...
UC Davis researchers identified a crucial mechanism that can cause cells to self-destruct. This new ability to trigger cell death could open ...
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